Publikationen

Pfad: Bioreact GmbH | Das Unternehmen | Publikationen

Publikationen

Wissenschaftliche Veröffentlichungen:

51. Tetsch L, Bend J, Hölker U, (2006) Molecular and enzymatic charakteristation of extra- and intracellular laccases from the acidophilic asciomycete Hortaea acidophila. Antonie van Leuwenhoek 90:183-194

50. Hölker U, Lenz J (2005) Solid state fermentation: Are there any biotechnological advantages? Current Opinion in Microbiology 8:301-306

49. Pokorný R, Olejnikova P, Balog M, Zifcak P, Hölker U, Janssen M, Bend, J, Hbfer M, Holiencin R, Hudecová D, Varecka L (2005) Characterisation of microorganisms isolated from lignite excavated from the coal-mine Zahorie (Southwestern Slovakia) Res. Microbiol 156:932-943

48. Manger-Jacob F, Müiller T, Janssen M, Höfer M, Hölker U (2005) Isolation and sequencing of a new glycoamylase gene from Aspergillus niger aggregate strain (DSM 823) molecular classified as A. tubingensis. Antonie van Leuwenhoek 88:267-275

47. Tetsch L, Bend J, Janssen M, Hölker U (2005) Evidence for functional laccases in the acidophhlc ascomycete Hortaea acidophila and isolation of laccase-specific gene fragments. FEMS Microbiol Let 245:161-168

46. Pokorný R, Vargovic P, Holker U, Janssen M, Bend J, Hudecová D, Varecka L (2005) Signaling pathway of light-induced conidiation in Trichoderma viride. J Basic Microbiol. (in press 45(3))

45. Hölker U, Bend J, Pracht R, Müller T, Tetsch L, Höfer M, de Hoog GS (2004) Hortea acidophila, a new acid-tolerant black yeast from lignite. Antonie van Leeuwenhoek _86:287-294

44. Hölker U, Höfer M, Lenz J (2004) Biotechnological advantages of laboratory-scale solid-state fermentation with fungi, Appl Microbiol Biotechnol 64: 175-186

43. Hölker U, Lenz J (2004) Enzym-Produktion in Festphasen-Prozessen, BIOspektrum 3: 269-270

42. Lenz J, Höfer M, Krasenbrink J-B, Hölker U (2004) A survey of computational and physical methods applied to solid-state fermentation, Appl Microbiol Biotechnol 65: 9-17

41. Lenz J, Hölker U (2004) Trickle-film processing: an alternative for producing fungal enzymes, BIOforum Europe 06: 55-57

40. Arenskötter M., Baumeister D., Bröker D., Hölker U., Ibrahim E.M.A., Lenz J., Rose K. & Steinbüchel A. (2003) Entwicklung eines biotechnologischen Verfahrens zur stofflichen Wiederverwertung kautschukhaltiger Rest- und Abfallstoffe. transkript 9. Jahrgang, Sonderband: 28-32.

39. Alt, W., Chaplain, M., Griebel, M., & Lenz, J. (eds.) Polymer and cell dynamics - Multiscale modelling and numerical simulation. Birkhäuser. Basel. 2003.

38. Lenz, J. & Felix, D. (2003) Multi-particle modelling of actin-myosin networks: From molecular interactions to cell motility. In: Alt, W., Chaplain, M., Griebel, M., and Lenz, J. (eds.) Polymer and cell dynamics - Multiscale modelling and numerical simulations. Birkhäuser. Basel. 2003. 75-89.

37. Hölker, U. (2003) Fermentation auf festen Substraten. BioTec. 3-4 32-33.

36. Hölker, U., Dickhaus, T. & Lenz. J. (2002) Novel solid state fermentation system and cultivation method for the sequential production of lignolytic enzymes. Proc. COST E23 "Biotechnology for improving pulp and paper processing", Grenobel, November 2002.

35. Hölker, U., Janssen, M., Lenz, J., Ludwig, S. & Höfer, M. (2002) Degradation of lignite by molds: Contribution of oxidative and hydrolytic enzymes. Proc. 15th International Congress of Chemical and Process Engeneering, Prague. ISBN 80-86059-33-2.

34. Hölker, U. & Höfer, M. (2002) Solid substrate fermentation of lignite by the coal solubilizing mould Trichoderma atroviride in a new type of bioreactor. Biotechnol. Let. 24 1643-1645.

33. Hölker, U., Dohse, J. & Höfer, M. (2002) Extracellular Laccase in the Trichoderma atroviride and Trichoderma harzianum. Folia Microbiol. 47 423-427.

32. Hölker, U., Schmiers, H., Winkelhöfer, M., Polsakiewicz, M., Ludwig, S., Dohse, J. and Höfer, M. (2002) Solubilization of low-rank coal by Trichoderma atroviride: Evidence for the involvement of hydrolytic and oxidative enzymes by using 14C-labeled lignite. J. Ind. Microbiol. Biotechnol. 28 207-212.

31. Lenz, J. (2001) Many-particle simulation of ameboid motility. Future Gener. Comput. Systems 17 863-872.

30. Klein, J., Fakoussa, R.M., Hölker, U., Hofrichter, M., Schmiers, H., Sinder & Steinbüchel, A., (2001) Biotechnology of Coal. in Biotechnology Vol. 10 Rehm, H.J, Reed Eds. ISBN 3-527-28320-X, 153-189.

29. Scheel, T., Hölker, U., Ludwig, S. & Höfer, M. (2000) Differential expression of mangenese peroxidase and laccase in white-rot fungi in the presence of manganese and aromatic compounds. Appl. Microbiol. Biotechnol. 54 686-691.

28. Hölker, U., Scheel, T., Ludwig, S. & Höfer, M. (1999) Potential Relevance of yeasts for the microbial processing of low-rank coal. Folia Microbiol. 44 226-227.

27. Hölker U., Ludwig, S., Scheel, T. & Höfer, M. (1999) Mechanisms of coal solubilization by the deuteromycetes Trichoderma atroviride and Fusarium oxysporum. Appl. Microbiol. Biotechnol. 52 57-59.

26. Höfer, M., Lenz, J., Heyer, M., Vacata, V. & Lichtenberg-Fraté, H. (1998) K+-fluxes through plasma membrane of Schizosaccharomyces pombe as measured by whole-cell patch clamp. Folia Microbiol. 43 195-197.

25. Scheel, T., Hölker, U., Ludwig, S. & Höfer, M. (1998) Evidence for and expression of the laccase gene in three basidiomycetes degrading humic acids. Appl. Microbiol. Biotechnol. 52 66-69.

24. Portele, A., Lenz, J. & Höfer, M. (1997) Estimation of membrane potential in reconstituted plasma membrane vesicles using a numerical model of Oxonol VI distribution. J. Bioenerg. Biomembr. 29 603-609.

23. Lenz, J., Höfer, M. & Sigler, K. (1997) Model of specific, apparently non-saturable solute uptake kinetics based on a carrier mechanism. Folia Microbiol. 42 234-236.

22. Schnabl, H., Hunte, C., Schulz, M., Wolf, D., Ghiena-Rahlenbeck, C., Bramer, M., Graab, M., Janssen, M., Kalweit, H. (1997) Microgravity affects the ubiquitin pools and actin isoforms of mesophyll protoplasts. ESA publication 105-108

21. Scheel, T., Mönkemann, H., Hölker, U., Ludwig, S. & Höfer, M. (1997) Molecular genetic characterization of three basidiomycetes which depolymerize humic acids. Proc. ICCS 1997 Eds.: Ziegler, A., van Heek, K.H., Klein, J. & Wanzel, W., P&W Druck und Verlag, Essen 1677-1679.

20. Mönkemann, H., Scheel, T., Ludwig, S., Hölker, U. & Höfer, M. (1997) Ligninolytic enzymes in the coal solubilizing deuteromycetes Trichoderma atroviride and Fusarium oxysporum. Proc. ICCS 1997 Eds.: Ziegler, A., van Heek, K.H., Klein, J. & Wanzel, W., P&W Druck und Verlag, Essen 1681-1684.

19. Hölker, U., Ludwig, S., Mönkemann, H., Scheel, T. & Höfer, M. (1997) Different strategies of fungi to solubilize coal: comparison of the deuteromycetes Trichoderma atroviride and Fusarium oxysporum. Proc. ICCS 1997 Eds.: Ziegler, A., van Heek, K.H., Klein, J. & Wanzel, W., P&W Druck und Verlag, Essen 1599-1602.

18. Mönkemann, H., Hölker, U. & Höfer, M. (1997) Components of a ligninolytic system in Fusarium oxysporum and Trichoderma atroviride. Fuel Process. Technol. 52 73-77.

17. Hölker, U., Mönkemann, H. & Höfer, M. (1997) A system to analyze the complex physiological states of coal solubilizing fungi. Fuel Process. Technol. 52 65-71.

16. Alt, W., Deutsch, A., Kamphuis A., Lenz, J. & Pfistner, B. (1996) Zur Entwicklung der Theoretischen Biologie: Aspekte der Modellbildung und Mathematisierung. In: Jahrbuch für Geschichte und Theorie der Biolgie, III (Hrsg.: Rheinberger, H.-J. und M. Weingarten). VWB - Verlag für Wissenschaft und Bildung. Berlin. 1996. 7-60.

15. Janssen, M., Hunte, C., Schulz, M., Schnabl, H. (1996) Tissue specification and intracellular distribution of actin isoforms in Vicia faba L. Protoplasma 191 158-163.

14. Schnabl, H., Hunte, C., Schulz, M., Wolf, D., Ghiena-Rahlenbeck, C., Bramer, M., Graab, M., Janssen, M., Kalweit, H. (1996) Effects of fast clinostat treatment and microgravity on Vicia faba L. mesophyll cell protoplast ubiquitin pools and actin isoforms. Microgravity Sci. Tec. 9 275-280.

13. Mönkemann, H., Hölker, U., Golubnitchaya-Labudová, O., Lichtenberg-Fraté, H. & Höfer, M. (1996) Molecular Evidence of a Lignin Peroxidase H8 Homologue in Fusarium oxysporum. Folia Microbiol. 41 445-448.

12. Lenz, J. (1995) Parameter optimization of membrane carrier models - An approach using evolutionary strategies. J. Biol. Syst. 3 155-164.

11. Hölker, U., Fakoussa, R. M. & Höfer, M. (1995) Growth substrates control the ability of Fusarium oxysporum to solubilize low-rank coal. Appl. Microbiol. Biotechnol. 44 351-355.

10. Portele, A., Lenz, J. and M. Höfer (1994) A method for estimating generated by the H+-ATPase of Schizosaccharomyces pombe in reconstituted plasma membrane vesicles. Folia Microbiol. 39 539-541.

9. Lenz, J. & Höfer, M. (1994) Ion channels as ion pumps - energy yield from environmental noise and local dynamic functional variability. Folia Microbiol. 3: 530-532.

8. Schulz M, Janssen M, Knop M, Schnabl H (1994) Stress and age related spots with immunoreactivity to ubiquitin-antibody of protoplast surfaces. Plant Cell Physiol. 35(4) 551-556.

7. Janssen, M., Hunte, C., Leineweber, K., Knop, M., Cramer, H., Traub, O., Schulz, M. (1994) Tissue and cell specific distribution of connexin 32- and connexin 26-related proteins from Vicia faba L. Bot. Acta 107 468-472.

6. Lenz, J. & Höfer, M. (1993) Evolutionary strategies and the optimization of carrier models. In: Modern trends in BioThermoKinetics (eds.: Schu-ster, S., Rigoulet, M., Ouhabi, R. and J.-P. Mazat). Plenum Press. New York and London. 1993. 77-81.

5. Hunte, C., Janssen, M., Schulz, M., Traub, O., Schnabl, H. (1993) Age dependent modifications and further localization of the cx-like protein from Vicia faba L. Bot. Acta 106 207-212.

4. Hölker, U., Ersek, T. & Höfer, M. (1993) Changes in ion fluxes and the energy demand during spore development in Phytophthora infestans zoospores. Folia Microbiol. 38 193-200.

3. Ersek, T., Hölker, U. & Höfer, M. (1991) Non-lethal immobilization of zoospores of Phytophthora infestans by Li+. Mycol. Res. 95 970-972.

2. Ingensiep, H. W. & Lenz, J. (1987) The mutations afila and acacia in connection with a model for the early phyllomorphogenesis of Pisum sativum. The Pisum Newsletter 19 15-16.

1. Lenz, J. & Ingensiep, H.W. (1987) Basis and proposals for a model in connection with the early phyllomorphogenesis of Pisum sativum. The Pisum Newsletter 19 25-27.

22. Hölker U (2007) , Enzymatische Aufbereitung von Biomasse für die Biogasverwendung - Ergebnisse aus dem NSBE-Projekt und aus der Praxis; International Energy Farming Congress Papenburg

21. Pesta G, Bochmann G, Lenz J, Hölker U, Meaer-Pittroff R (2005) Die Verzuckerung von zellulosehaltigen Rohstoffen durch Mischenzyme zur Steigerung der spezifischen Biogasausbeute, VDI Wissensforum, 3. Fachtagung Biogas, Osnabrück

20. Hölker U (2004) Der lange Weg von der Ausgründung bis zum ersten Erfolg, Bio[tech]nik - Investition Zukunft, Vdbiol Jahrestagung/Bonn

19. Hölker U, Lenz J (2004) Enzyme production in solid-state bioprocessing, BioPerspectives, Wiesbaden

18. Bend J, Hölker U (2003) Laccases in melanised fungi, Workshop der VAAM-Fachgruppe Mycologie 'Fungi in Ecology and Biotechnology', Göttingen

17. Bend J, Tetsch L, Pracht R, Höfer M, Hölker U (2003) Isolation and physiological characterization of a new pH-tolerant black yeast, VAAM-Tagung, Berlin

16. Hölker U, Dickhaus T, Lenz J (2003) Novel solid-state fermentation system and cultivation method for the sequential production of lignolytic enyzmes, DECHEMA Jahrestagung der Biotechnologen, Wiesbaden

15. Tetsch L, Bend J, Pracht R, Höfer M, Hölker U (2003) Characterization of a laccase participating in the synthesis of melanin isolated from a acidophilic black yeast, VAAM-Tagung, Berlin

14. Tetsch L, Janssen M, Hölker U (2003) In search fo the laccase genes of Hortaea acidophila, Workshop der VAAM-Fachgruppe Mycologie 'Fungi in Ecology and Biotechnology', Göttingen

13. Hölker, U., Janssen, M., Lenz, J., Höfer, M. (2002) Degradation of lignite by molds: Contribution of oxidative and hydrolytic enzymes. CHISA, Prague.

12. Lenz, J., Janssen, M., Ludwig, S., Hölker, U. (2002) Coherent two-phase process for anaerobic and aerobic fermentation of solid substrates within a single bioreactor. CHISA, Prague.

11. Hölker, U., Dickhaus, T., Janßen, M., Ludwig, S, Lenz, J. (2002) Rieselfilmverfahren mit periodischer Extraktion zur kontinuierlichen Produktion extrazellulärer pilzlicher Enzyme.

10. Lenz, J., Janssen, M., Ludwig, S. & Hölker, U. (2002) 2-Phasen-Verfahren zur anaeroben und aeroben Fermentation fester Substrate in einem Bioreaktor. LifeCom, Düsseldorf.

9. Ludwig, S., Schinke, S., Scheel, T., Höfer, M. & Hölker, U. (1999) Differential analysis of fungal extracellular enzymes induced by lignite on protein and mRNA level. Proc. Seventh International Symposium on Biological Processing of Fossil Fuels. Madrid, Spain.

8. Hölker, U., Polsakiewicz, M., Scheel, T., Ludwig, S., Schinke, S. & Höfer, M. (1999) Coal as inductor of esterases in the deuteromycete Trichoderma atroviride. Proc. Seventh International Symposium on Biological Processing of Fossil Fuels. Madrid, Spain.

7. Scheel, T., Hölker, U., Ludwig, S., Schinke, S. & Höfer, M. (1999) Expression of laccase and mangan peroxidase in basidiomycetes in the course of humic acid degradation. Proc. Seventh International Symposium on Biological Processing of Fossil Fuels. Madrid, Spain.

6. Hölker, U. & Höfer, M. (1999) Attempt to scale up microbial solubilization of lignite in a 25- liter bioreactor. Proc. Seventh International Symposium on Biological Processing of Fossil Fuels. Madrid, Spain.

5. Scheel, T., Ludwig, S., Hölker, U. & Höfer M. (1998) Regulation of laccase and mangan peroxidase in white rot fungi. Workshop der VAAM-Fachgruppe Mycologie "Fungi in Ecology and Biotechnology" Tagungsband S. 68.

4. Ludwig, S., Schinke, S., Scheel, T., Hölker, U. & Höfer, M. (1998) Induction of coal solubilizing enzymes in the deuteromycete Trichoderma atroviride Workshop der VAAM-Fachgruppe Mykologie "Fungi in Ecology and Biotechnology" Tagungsband S. 66.

3. Hölker U., Scheel, T., Ludwig, S. & Höfer. M. (1998). Metabolism of 14C-labelled lignite by the coal solubilizing deuteromycete Trichoderma atroviride. Workshop der VAAM-Fachgruppe Mykologie "Fungi in Ecology and Biotechnology" Tagungsband S. 25.

2. Hölker, U., Mönkemann, H., Scheel, T. & Höfer, M. (1996) Metabolic regulation of coal solubilizing ability in the fungi Fusarium oxysporum and Trichoderma atroviride. VAAM-Workshop: Regulation in Fungi. Phenomena and Mechanisms. Jülich. Tagungsband S. 25.

1. Hölker, U., Mönkemann, H. & Höfer, M. (1995) Kohleverflüssigung durch Fusarium oxysporum. VAAM-Workshop: Fungal Metabolism and Degradation of Natural and Synthetic Compounds. Kaiserslautern. Tagungsband.

Bioreact GmbH (2004) Bioreactor for fermenting solids, US 6,797,508 B1

Bioreact GmbH (2004) Bioreactor for fermenting solids, EP 1 392 813 A2

Bioreact GmbH (2004) Bioreaktorsystem zur Nutzung der Wärmeentwicklung biochemischer Reaktionen, EP 1 421 171 A2

Bioreact GmbH (2003) Neuartiger Rieselbett-Bioreaktor mit Wirbelbett-Regeneration, DE 10206772 A1

Bioreact GmbH (2003) Bioreactor for fermenting solids, SA 2002/2036

Bioreact GmbH (2003) Bioreaktor mit wenigstens zwei Reaktionskammern, DE 101 27 869 A1

Bioreact GmbH (2003) Cultivation method for micro-organisms and bioreactor, WO 2003/070873 A3

Bioreact GmbH (2003) Bioreaktorsystem zur Nutzung der Wärmeentwicklung biochemischer Reaktionen, DE 101 39 248 A1

Bioreact GmbH (2002) Bioreactor having at least two reaction chambers, WO 02/100999 A3

Hölker U (2002) Bioreaktor zur Fermentierung fester Stoffe, EP 1 212 402 A1

Franken E.M., Janssen M., Schindler M., Tietjen K., Moras D., Wurtz J., Rochel-Guiberteau N., Billas I. (2002) Ligand-binding domain of the ultraspiracle (USP) protein. DE10036461A, US2003/0027984A1, EP1176152A3

Zitzmannn W., Franken E.M., Janssen M., Schulte T. (2002) Heliothis virescens ultraspiracle (USP) protein. DE10036469A, US2002/0037556A1, EP1182212A3.

Hölker U (2001) Bioreaktor zur Fermentierung fester Stoffe, DE 199 43 853 A1

Hölker U (2000) Bioreactor for fermenting solids, PCT WO 01/19954